The National Institutes of Health (NIH) has awarded Pain Therapeutics a $1.7 million research grant to study PTI-125 as a potential treatment for Alzheimer’s disease. PTI-125 is an oral, small molecule drug developed by the Austin, Texas-based company in collaboration with other partners. It has been shown to significantly improve…
Insightec’s new platform, Exablate Neuro, is to be a part of the first-ever clinical trial (NCT02986932) evaluating the safety and feasibility of opening the blood-brain barrier (BBB) in Alzheimer’s disease patients at Sunnybrook Health Sciences Centre in Toronto, Canada. Exablate Neuro uses a technique called…
A Keck School of Medicine of USC study shows that cognitive tests can detect early Alzheimer’s disease in older adults who do not present symptoms yet. The study “Detectable Neuropsychological Differences in Early Preclinical Alzheimer’s Disease: A Meta-Analysis” was published in the journal Neuropsychology Review. It is…
Two surveys released today — the start of Alzheimer’s disease month — examine the emotional toll the condition places on caregivers, and their need for greater support. The results are both revealing and alarming. The online survey by the Alzheimer’s Association also delves into the serious lack of preparedness among the public,…
Acadia Pharmaceuticals plans to start a Phase 3 clinical program to explore the effect of Nuplazid (pimavanserin) in Alzheimer’s disease patients with psychosis. The medication was approved by the U.S. Food and Drug Administration in April 2016 to treat similar problems with Parkinson’s patients. “We’re very pleased with…
In a recent Morbidity and Mortality Weekly Report from the Centers for Disease Control and Prevention (CDC), researchers show that deaths due to Alzheimer’s disease increased almost 55% between 1999 and 2014. Also, more patients are perishing at home, which likely will increase the burden on family members or…
Researchers have discovered a common link between abnormal proteins that cause damage to brain cells in Alzheimer’s (AD), Parkinson’s (PD) and Huntington’s (HD) disease patients. The discovery could help scientists understand the mechanism by which these neurodegenerative diseases spread, and possibly lead to a therapy…
A new DNA vaccine protects against accumulation of toxic proteins in Alzheimer’s disease, according to new research. One study, “Evaluation of a DNA Aβ42 Vaccine in Aged NZW Rabbits: Antibody Kinetics and Immune Profile after Intradermal Immunization with Full-Length DNA Aβ42 Trimer,” appeared in the Journal of Alzheimer’s…
Otsuka America Pharmaceutical and Avanir Pharmaceuticals are working with southern New Jersey educational administrators to create specialists who can help Alzheimer’s patients and their families navigate the care continuum. The goal is to start a one-year training program at Camden County College that leads to a specialist’s certification. Those receiving…
Epileptic-seizure-like activity in a brain region called the hippocampus may contribute to the development of Alzheimer’s, according to a case study involving two patients. And an anti-epileptic medicine may be able to slow the disease’s progression, Massachusetts General Hospital researchers said. An additional finding was that seizure-like activity may be difficult to…
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