Memory Performance Linked To Key Genetic Variant

Memory Performance Linked To Key Genetic Variant
shutterstock_141503410In neurodegenerative disorders such as Alzheimer's Disease, the loss of memory is often a defining symptom. In a study entitled “FASTKD2 is associated with memory and hippocampal structure in older adults” the authors report to have found a new genetic variant in the FASTKD2 gene that is associated with improved memory performance. The new findings could give rise to future drug development for treating dementia and Alzheimer's. The study was published in the Molecular Psychiatry journal. The team of researchers at the Indiana University School of Medicine with study first author, Vijay K. Ramanan, Ph.D., and led by Andrew J. Saykin, Psy.D., director of the Indiana Alzheimer Disease Center and the IU Center for Neuroimaging performed a genome-wide screen, to find new genetic markers of memory impairment, a fundamental feature of Alzheimer’s disease. Additionally, the authors analyzed memory test results of 14,000 older adults. They found a single alteration in the DNA sequence, known as a single nucleotide polymorphism (SNP), in a gene. FASTKD2 (short for fast-activated serine/threonine kinase domains 2), was associated with better resul
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