Clinical Trial Reveals Promising Brain Therapeutic Drug for the Pre-Dementia Stage of Alzheimer’s Disease

Clinical Trial Reveals Promising Brain Therapeutic Drug for the Pre-Dementia Stage of Alzheimer’s Disease
hippocampusPharmaceutical company AgeneBio recently announced the publication of results of a Phase 2 clinical trial based on the company's therapeutic product AGB101 for the pre-dementia stage of Alzheimer’s disease in the journal NeuroImage: Clinical. The study entitled “Response of the medial temporal lobe network in amnestic mild cognitive impairment to therapeutic intervention assessed by fMRI and memory task performance” was conducted by researchers at Johns Hopkins University in Baltimore and supported by the National Institutes of Health (NIH). Alzheimer’s disease is an age-related, neurodegenerative disorder where individuals initially experience memory loss and confusion that gradually leads to behavior and personality changes, a decline in cognitive abilities, and ultimately the severe loss of mental function. Alzheimer’s disease is characterized by the formation of amyloid plaques in the brain and the loss of neurons that are responsible for memory and learning. It is estimated that by age 85, one in every three individuals will have Alzheimer’s disease. Currently, 25 million people worldwid
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