In a recent study entitled “Central Cholinergic Neurons Are Rapidly Recruited by Reinforcement Feedback” and published in Cell, Cold Spring Harbor Laboratory researchers found that cholinergic neurons play a key role in the response to unexpected triggers. Cholinergic neurons are nerve cells which mainly use the neurotransmitter acetylcholine…
A study published in the journal Nature Neuroscience revealed new insights into the role played by astrocytes in neurological disorders such as Alzheimer’s disease. The study was conducted by an international research team and is entitled “Nuclear pore complex remodeling by p75NTR cleavage controls…
An international team led by researchers at The Rockefeller University and Columbia University recently published in the journal Nature Medicine a novel mechanism through which it is possible to decrease the production of beta-amyloid protein, a key factor in Alzheimer’s disease development. The study is…
A study recently published in the journal Neuropsychopharmacology revealed that the inhibition of a gene called phosphodiesterase-4B (PDE4B) in mice enhances the animals’ cognitive abilities. The work was conducted by an international team of researchers and is entitled “Specific Inhibition of Phosphodiesterase-4B Results in Anxiolysis…
A study recently published in the Journal of Alzheimer’s Disease revealed that intranasal administration of insulin can be a potential therapeutic strategy for Alzheimer’s disease and dementia conditions. The study entitled “Central Nervous System Delivery of Intranasal Insulin: Mechanisms of Uptake and Effects on…
Alzheimer’s disease is a neurodegenerative disorder characterized by cognitive and behavioral problems. It is the most common form of dementia in the elderly with patients initially experiencing memory loss and confusion that gradually leads to behavior and personality changes, a decline in cognitive abilities and ultimately to severe loss of…
Researchers at New York University Langone Medical Center and the Nathan S. Kline Institute for Psychiatric Research (NKI) in New York recently discovered a potential therapeutic target for Alzheimer’s disease and provided more insight into the associated endosome dysfunction. The study was published in the journal…
Researchers at Cedars-Sinai Medical Center recently published in the journal Brain a new promising immune therapeutic strategy for Alzheimer’s disease using mice models. The study is entitled “Therapeutic effects of glatiramer acetate and grafted CD115+ monocytes in a mouse model of Alzheimer’s disease”.
Researchers at Newcastle University in the United Kingdom recently revealed their findings on alterations in the brain network of patients with disorders linked to dementia, namely dementia with Lewy bodies (DLB) and Alzheimer’s disease. The study was published in the journal Neurobiology of Aging and is…
Researchers at the Hospital de Magalhães Lemos and the Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto in Portugal recently revealed that a patient’s ability to cope with the neurodegenerative process in disorders like Alzheimer’s disease can influence disease severity. The study is entitled “…
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