Men Exhibit Worse Memory Performance than Women During the Aging Process

Men Exhibit Worse Memory Performance than Women During the Aging Process
hippocampusResearchers at the Mayo Clinic and Foundation in Minnesota revealed that within the natural aging process, men have worse memory performance than women. The study was recently published in the journal JAMA Neurology and is entitled “Age, Sex, and APOE ε4 Effects on Memory, Brain Structure, and β-Amyloid Across the Adult Life Span.” Changes in cognitive performance are part of the natural aging process. In this study, researchers assessed memory performance and brain structure in individuals according to their hippocampal volume (a region in the brain linked to memory and spatial navigation) and the presence of amyloid plaques in the brain. Amyloid plaques are aggregates of amyloid proteins that are associated with Alzheimer’s disease, an age-related neurodegenerative disorder where individuals suffer a decline in cognitive abilities, behavior and personality changes, and ultimately severe loss of mental function. Also associated to Alzheimer's disease is the APOE ε4 gene, a risk factor for Alzheimer’s development that has been shown to significantly reduce the age of onset for this disorder. Researchers have hypothesized that the presence of amyloid plaques and APOE ε4 allele a
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