A4 study on Alzheimer’s disease is Recruiting African-American Volunteers

A4 study on Alzheimer’s disease is Recruiting African-American Volunteers
shutterstock_121061185A new study, entitled Anti-Amyloid in Asymptomatic Alzheimer’s study, simply referred to as the A4 study, is currently recruiting African-American volunteers that have already developed brain alterations as a result of Alzheimer’s disease but that have not yet developed symptoms. The study aims to decrease the progression of Alzheimer’s-induced brain damage and associated memory loss before the onset of disease symptoms. The study focuses on African-Americans since it is established that they exhibit two to three times higher risk to develop Alzheimer’s when compared to caucasian Americans. Multiple institutions, including the National Institute on Aging, the primary Federal agency supporting and conducting Alzheimer's disease research, Eli Lilly and Company, and other philanthropic organizations are funding the A4 Study. In the A4 study, researchers are testing an investigational drug that targets the protein amyloid, a known and established factor that by accumulating into amyloid plaques in brains’ neurons leads to their death, prompting the onset of Alzheimer's. The drug is expected to delay the progressive memory loss associated with Alzheimer’s by targeting the deposition of amyloid plaques into patients’ brains. Reisa Sperling, MD, principal investigator o
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