Arginine May Be A Cause and Therapeutic Target for Alzheimer’s Disease in Mice

Arginine May Be A Cause and Therapeutic Target for Alzheimer’s Disease in Mice
neuronsA new study published in the Journal of Neuroscience revealed that specific immune cells and degradation of a nutrient called arginine might be linked to Alzheimer’s disease development. The study was performed by researchers at Duke University Medical Center, the West Virginia University School of Medicine and the University of Washington, and is entitled “Arginine Deprivation and Immune Suppression in a Mouse Model of Alzheimer's Disease.” Alzheimer's disease is a neurodegenerative disorder where individuals initially experience memory loss and confusion that gradually leads to behavior and personality changes, a decline in cognitive abilities, and ultimately the severe loss of mental function. The disease is characterized by the loss of neurons responsible for memory and learning, and brain formation of amyloid plaques (containing sticky beta-amyloid proteins) and tangles (twisted strands of a protein called tau). The body’s immune system is thought to play a role in Alzheimer’s disease pathogenesis, although the link between immunity and this neurodegenerative disorder is not clear. In this study,
Subscribe or to access all post and page content.