In Early Alzheimer’s Disease, Impaired Blood-Brain Barrier May Lead to Cognitive Decline, Researchers Say

In Early Alzheimer’s Disease, Impaired Blood-Brain Barrier May Lead to Cognitive Decline, Researchers Say
Researchers at the Maastricht University Medical Center have investigated how the permeability of the blood-brain barrier (BBB) is involved in early forms of Alzheimer disease. The findings suggest that a faulty BBB may be involved in the initial pathologic process that eventually results in neurodegeneration and dementia in these patients. Researchers believe that detecting blood-brain barrier leakage may lead to earlier diagnoses. The research paper, “Blood-Brain Barrier Leakage in Patients with Early Alzheimer Disease,” was recently published in Radiology. The blood-brain barrier, made up of specialized and tightly packed endothelial cells,
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