Canola Oil Worsens Memory and Learning Ability of Mice with Alzheimer’s, Study Shows

Canola Oil Worsens Memory and Learning Ability of Mice with Alzheimer’s, Study Shows
Giving mice with Alzheimer's a canola oil-rich diet for six months led to their memory and learning ability worsening, a study reports. The research, “Effect of canola oil consumption on memory, synapse and neuropathology in the triple transgenic mouse model of Alzheimer’s disease,” was published in the journal Scientific Reports. Claims that the rapeseed extract canola oil is good for health, particularly the heart, has led to a jump in its consumption in recent years. But little research has been done on whether the claims are true. "Canola oil is appealing because it is less expensive than other vegetable oils, and it is advertised as being healthy," Dr. Domenico Praticò, an Alzheimer's expert at Temple University's Lewis Katz School of Medicine, said in a press release. "Very few studies, however, have examined that claim, especially in terms of the brain." Pratico's team used a mouse model of Alzheimer's to investigate canola's effect on the formation of two harmful brain structures — amyloid protein clumps and twisted masses of proteins known as neurofibrillary tangles. Scientists have connected the two with the nerve cell degeneration and memory loss in Alzheimer's. The mice displayed the human features of Alzheimer's, and their condition deteriorated with age. When they were six months old, researchers divided them into two groups. They fed one group a normal diet and the other a diet supplemented with a tablespoon of canola oil a
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