Phase 3 of Large-scale Alzheimer’s Disease Study Looking to Enroll Hundreds of Participants

Phase 3 of Large-scale Alzheimer’s Disease Study Looking to Enroll Hundreds of Participants
The Alzheimer’s Disease Neuroimaging Initiative (ADNI) is searching for participants to enroll in one of the largest and longest trials on Alzheimer’s disease. This ongoing study aims to develop biomarkers for the early detection and tracking of Alzheimer’s over time. Researchers need to enroll approximately 800 participants, between 55 and 90 years old, across 60 sites in the United States and Canada. The study is looking healthy volunteers without memory problems, people with mild memory impairments, and patients diagnosed with mild dementia due to Alzheimer’s disease. There is no medication involved. “One of the biggest challenges researchers face is finding people to volunteer to take part in studies,” Michael Weiner, MD, principal investigator of the study, said in a press release. “We can beat Alzheimer’s, but we can’t do it without volunteers. We need help." ADNI, funded by the National Institutes of Health, was launched in 2004, and has helped validate biomarkers for the disease, including blood tests, cerebrospinal fluid tests, and imaging with magnetic resonance imaging (MRI) and positron emission tomography (PET) scans. Now in its third phase, ADNI3 (NCT02854033) intends to determine the relationships between the clinical, cognitive, imaging, genetic,
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