Alzheimer’s Animal Studies Examine Lack of ‘Cleaning’ in Brain Cells

Alzheimer’s Animal Studies Examine Lack of ‘Cleaning’ in Brain Cells
Boosting mitophagy — a natural process that clears neurons from damaged mitochondria (cells' energy powerhouses) — decreased amyloid plaque formation and reversed cognitive deficits, namely memory impairments, across different animal models of Alzheimer’s disease (AD). "When the cleaning system does not work properly, there will be an accumulation of defective mitochondria in the brain cells. And this may be really dangerous. At any rate, the poor cleaning system is markedly present in cells from both humans and animals with Alzheimer's. And when we improve the cleaning in live animals, their Alzheimer's symptoms almost disappear," Vilhelm Bohr, study co-lead author, said in a press release. Bohr is af
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