Researchers Link High Levels of Aluminum to Amyloid-Beta in Same Brain Regions of Those With Familial Alzheimer’s

Researchers Link High Levels of Aluminum to Amyloid-Beta in Same Brain Regions of Those With Familial Alzheimer’s
Researchers have found large deposits of aluminum and amyloid-beta — the protein that forms toxic aggregates in the brain and is thought to be involved in the onset of Alzheimer’s disease — in the same brain regions of patients with familial Alzheimer’s. Their findings point towards a close relationship between brain aluminum content and the levels of amyloid-beta, possibly modulated by genetic factors that predispose individuals to the disease. The research was published in a study, “Aluminum and Amyloid-β in Familial Alzheimer’s Disease,” in the Journal of Alzheimer's Disease. For more than 40 years, studies have suggested that aluminum and amyloid-beta are associated with each. Both are considered major risk factors for Alzheimer’s. In a previous study, the same group of researchers discovered large amounts of aluminum in the brain of patients with familial Alzheimer’s, an inherited form of the disease caused by mutations in certain genes. To investigate the possible relationship between aluminum and amyloid-beta, these investigators, from
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