Posts by: Charlotte Baker

News

Researchers have found that amyloid, the protein that forms toxic aggregates, or clumps in the brain and is thought to be involved in the onset of Alzheimer’s disease (AD), accumulates ... Read more

February 26, 2020February 26, 2020

DNA from Bacteria in Brain May Promote Tau Clumping, Study Suggests

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DNA from various species of bacteria, some of which — like E. coli — have been identified in the brains of Alzheimer’s patients, can cause the tau protein to fold incorrectly ... Read more

February 21, 2020February 21, 2020

Solanezumab and Gantenerumab Fail to Slow Memory Loss or Cognitive Decline in Early-onset Alzheimer’s, Study Finds

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Two investigational treatments, solanezumab and gantenerumab, failed to prevent memory loss or cognitive decline in patients with a rare, inherited form of early-onset Alzheimer’s disease, who were enrolled in a ... Read more

February 14, 2020February 14, 2020

Scientists Use CRISPR-Cas9 as ‘DNA Scissors’ to Cut Out Alzheimer’s Gene in Mice, Study Shows

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Using the gene editing technology CRISPR-Cas9 like a pair of “DNA scissors,” researchers were able to essentially cut out the beta-secretase 1 (BACE1) gene in a mouse model of Alzheimer’s ... Read more

February 12, 2020February 12, 2020

Chaperone Works to Lessen Alzheimer’s Symptoms and Toxic Protein Buildup, Mouse Study Says

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A molecular chaperone called TPT-172 was able to prevent proteins linked to Alzheimer’s — including amyloid-beta and tau — from building up in the brain, improve memory and ease brain inflammation when tested in ... Read more

February 5, 2020February 5, 2020

Phase 1b Trial Begins to Test Alector’s Immune-system Targeting Antibody AL003 in Alzheimer’s Patients

News

A Phase 1b trial has started dosing Alzheimer’s patients with Alector’s candidate immune system-targeting therapy, called AL003, to evaluate its safety and tolerability, the company has announced. AL003 is an ... Read more

February 3, 2020February 3, 2020

Researchers Link High Levels of Aluminum to Amyloid-Beta in Same Brain Regions of Those With Familial Alzheimer’s

News

Researchers have found large deposits of aluminum and amyloid-beta — the protein that forms toxic aggregates in the brain and is thought to be involved in the onset of Alzheimer’s disease ... Read more

January 28, 2020January 28, 2020

Soybean Oil Can Disrupt Genes in Brain in Ways Linked to Disease, Mouse Study Finds

News

Soybean oil, an increasingly common cooking oil, especially in the United States, can cause changes in the brain that could be linked to diabetes, inflammation, and brain disorders, an early ... Read more