Alice Melão,  —

AbbVie and Alector are partnering on developing and commercializing treatments for Alzheimer’s and other neurodegenerative diseases. Alector brings an immuno-neurology discovery platform to the partnership. AbbVie brings its expertise in research, development, and commercialization of therapies targeting Alzheimer’s. It has become increasingly clear that the immune system plays a key…

The U.S. Food and Drug Administration has granted Fast Track status to Alzheon’s Alzheimer’s therapy candidate ALZ-801, which studies have shown prevents the clustering of harmful proteins associated with the disease. “We look forward to working closely with the FDA as we seek to make progress in developing a…

A person’s awareness of a cognitive problem, such as memory loss, may be a good indication that he or she is not going to develop Alzheimer’s disease. According to a study conducted by researchers at the Centre for Addiction and Mental Health (CAMH) in Toronto, Canada, people who are unaware…

The Alzheimer’s Drug Discovery Foundation and Pfizer’s Centers for Therapeutic Innovation are  supporting a Johns Hopkins University School of Medicine effort to develop therapies for Alzheimer’s, Parkinson’s, and other neurodegenerative diseases. Valina Dawson, a neurology professor who is co-director of neuroregeneration and stem cell programs at Johns Hopkins’ Institute for Cell Engineering, will…

Menopause triggers numerous changes in a woman’s body — and, apparently, metabolic changes in the brain as well that puts middle-age women at greater risk of Alzheimer’s disease, a study reports. This finding provides new insights into why women have a higher incidence of this neurological disease, even when a…

Investigators at University of North Texas Health Science Center (UNTHSC) in Fort Worth want to understand why people of Hispanic descent develop cognitive loss and Alzheimer’s disease earlier than non-Hispanics. Their new study, funded by a $12 million grant from the National Institutes of Health, aims to add knowledge…

Researchers at Virginia Commonwealth University (VCU) have found that the presence of two additional amino acids in the amyloid beta (Aβ) protein sequence forms the basis of amyloid plaque formation and Alzheimer’s disease development. Their study, “Few Ramachandran Angle Changes Provide Interaction Strength Increase in Aβ42 versus Aβ40 Amyloid Fibrils,” appeared…

More 100 neurologists, other scientists and disease advocates are supporting the Alzheimer’s Breakthrough team in its goal of getting “launched” at next month’s XPRIZE summit. Their effort centers on crowdsourcing, attracting a worldwide spectrum of experts and innovators to develop new technologies focused on brain health. These technologies encompass artificial intelligence, biotechnology, precision pharmaceuticals, physics…

Researchers of two independent studies have discovered how a specific mutation on the TREM2 gene contributes to the development and progression of Alzheimer’s disease, findings that shed light on the role of TREM2 in the brain, and can lead to new ways of treating this neurological disease. Their work was reported in studies titled…

The naturally occurring hormone klotho improved cognition in mouse models of Alzheimer’s and Parkinson’s disease, according to a University of California medical center study. Researchers said the findings could lead to new therapies for the neurological disorders. The study that the team published in Cell Reports was titled “Peripheral Elevation of a Klotho…