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January 21, 2019January 21, 2019

Poor Sleep Quality in Older People Linked to Early Signs of Alzheimer’s

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People 60 or older with a disrupted pattern of deep sleep — the one that helps memory formation — have a higher accumulation of the Alzheimer’s hallmark tau protein in ... Read more

January 18, 2019January 18, 2019

African-Americans with Alzheimer’s Have Lower Expression of 2 Common Biomarkers, Study Finds

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African-Americans have lower expression of two biomarkers of Alzheimer’s, suggesting a possible race-dependent biological mechanism that contributes to the development of the disease, a study shows. This discrepancy between ... Read more

January 16, 2019January 16, 2019

Top 10 Alzheimer’s Disease Stories of 2018

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Throughout 2018, Alzheimer’s News Today brought you stories of important discoveries, treatment developments, clinical trials, and other events related to Alzheimer’s disease. As we look forward to providing more news to ... Read more

January 14, 2019January 14, 2019

Choline-enriched Diet May Help Reduce Alzheimer’s Risk Across Generations, Mouse Study Finds

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A maternal diet supplemented with choline, an essential nutrient, reduced the number of amyloid plaque deposits and improved memory across two generations of a mouse model of Alzheimer’s disease, a ... Read more

January 11, 2019January 11, 2019

Small Molecule Originally Developed to Treat Depression Improved Memory in Alzheimer’s Mouse Study

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A small molecule delivered orally for 56 days improved memory in mice carrying the ApoE4 gene, the most common genetic risk factor for Alzheimer’s disease. The molecule, called A03 and ... Read more

January 9, 2019January 9, 2019

Alzheimer’s Initiative Widens Research Focus on Frontotemporal Degeneration With New $5M Commitment

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With a new $5-million commitment, the Alzheimer’s Drug Discovery Foundation’s (ADDF) Diagnostics Accelerator initiative is expanding its focus on frontotemporal degeneration, the most common form of dementia for individuals under ... Read more

January 7, 2019January 7, 2019

Salt, Acidic Conditions Promote Alzheimer’s Hallmark Amyloidosis, Study Shows

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Salt together with acidic conditions can change the 3D structure of the beta2-microglobulin protein and promote the formation of amyloid fibrils — a hallmark of Alzheimer’s disease. The study, ... Read more

January 4, 2019January 4, 2019

NHE6 Inhibition Could Help Prevent Late-onset Alzheimer’s, Researchers Say

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Inhibiting a protein called NHE6 is a potential strategy to prevent the damaging effect of ApoE4 and the associated risk of late-onset Alzheimer’s disease, a study suggests. The study, ... Read more

December 21, 2018December 21, 2018

Gene That Makes Neurons Vulnerable to Abnormal Levels of Tau Protein Identified in Study

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A study has identified the gene that explains why excitatory neurons — brain cells that excite their targets — are more vulnerable to accumulations of abnormal tau protein aggregates, ... Read more

December 19, 2018December 19, 2018

Maintaining Active Brain May Slow Cognitive Decline in Neurodegenerative Disorders, Study Shows

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An intellectually active lifestyle may help protect against neurodegeneration, delaying symptoms and loss of the brain’s gray matter, which is essential for motor control and sensory perception, a study ... Read more

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