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October 21, 2019October 21, 2019

Targeting Single Enzyme May Produce Multiple Benefits for Alzheimer’s, Mouse Study Suggests

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Targeting a single enzyme called PI3K-delta prevented neuroinflammation, reduced the accumulation of toxic amyloid-beta plaques in the brain, and prevented memory deficits in a mouse model of Alzheimer’s disease, ... Read more

October 18, 2019October 18, 2019

Alzheimer’s Patient Reverted Back to Earlier Writing Style after Diagnosis, Reveals Analysis of Woman’s Long-term Journals

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The writing style of a woman’s diary entries over 31 years has given researchers a glimpse into the progression of her cognitive decline from Alzheimer’s disease, revealing a relationship ... Read more

October 16, 2019October 16, 2019

Oral Anticoagulant Dabigatran Prevented Memory Loss in Mouse Model of Alzheimer’s, Study Shows

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Oral treatment over one year with an approved blood thinner called dabigatran prevented memory loss, preserved blood circulation in the brain and reduced the amount of senile plaques in ... Read more

October 14, 2019October 14, 2019

Long-term Extension Study of Anavex 2-73, Potential Treatment of Alzheimer’s Dementia, Opens

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Anavex Life Sciences has launched an extension study — called ATTENTION-AD — to investigate the long-term safety and efficacy of Anavex 2-73 in delaying cognitive decline in people with ... Read more

October 11, 2019October 11, 2019

Nuplazid Significantly Delays Relapses in Dementia-related Psychosis, Phase 3 Study Shows

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Treatment with Nuplazid (pimavanserin) significantly delays time to a psychosis relapse in people with dementia-related disorders such as Alzheimer’s and Parkinson’s diseases, according to results from the ongoing Phase 3 HARMONY study. Evaluation ... Read more

October 9, 2019October 9, 2019

NDX-1017 Phase 1 Trial Complete, Results Will Be Presented at CTAD Conference, Athira Says

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Athira Pharma has completed the Phase 1 trial testing NDX-1017, its lead therapeutic candidate for Alzheimer’s disease, and will present the results at the 12th Annual Clinical Trials on Alzheimer’s ... Read more

October 7, 2019October 7, 2019

NIA Launches Research Centers to Advance Drug Discovery in Alzheimer’s

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To advance the pipeline for innovative therapeutics in Alzheimer’s (AD), the National Institute on Aging (NIA) will invest an expected $73 million over five years in two new translational research ... Read more

October 4, 2019October 4, 2019

$53M NIA Grant Will Test Alzheimer’s Care in Real-world Settings

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The National Institute on Aging (NIA) has awarded a five-year grant expected to total $53.4 million to Brown University and Hebrew SeniorLife to lead the creation and management of ... Read more

October 2, 2019October 2, 2019

Carefully Targeting Brain Immune Cells May Help Prevent Amyloid-beta Plaques, Study Suggests

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Therapeutics that target brain immune cells known as microglia may prevent the formation of amyloid-beta plaques, one of the hallmarks of Alzheimer’s disease, according to a recent mouse study. ... Read more

September 30, 2019September 30, 2019

Free Online Series Explores Alzheimer’s, Treatment Challenges and Ways of Lowering Risk

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An upcoming and free web-based documentary series explores why efforts to develop an Alzheimer’s therapy are so challenging and often end in failure, and how individuals can lower their disease risk. ... Read more

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