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October 21, 2020October 21, 2020

RetiSpec and Gentex Developing Technology to Detect Early Alzheimer’s

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RetiSpec and Gentex are partnering to develop a technology to detect Alzheimer’s disease — potentially years before symptom onset — using a non-invasive and cost-effective eye scan technique. The partnership ... Read more

October 19, 2020October 19, 2020

First Patient Dosed in Phase 2 Trial of Bryostatin-1 in Long-term Use

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A first patient has been dosed in a Phase 2 trial investigating the safety and long-term efficacy of bryostatin-1 in treating moderate and moderately severe Alzheimer’s disease, the therapy’s ... Read more

October 14, 2020October 14, 2020

GemVax Seeks Expanded Access for Mild Alzheimer’s for Planned GV1001 US Trial

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GemVax & KAEL has filed for expanded access of its U.S. Food and Drug Administration (FDA) investigational new drug (IND) application for GV1001, its experimental treatment for Alzheimer’s disease. ... Read more

October 12, 2020October 12, 2020

Dosing Starts in Phase 2/3 Trial of Athira’s ATH-1017 for Alzheimer’s

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Dosing of patients has begun in a Phase 2/3 clinical trial evaluating ATH-1017, Athira Pharma‘s investigational candidate for the treatment of mild to moderate Alzheimer’s disease. “Embarking on this ... Read more

October 7, 2020October 12, 2020

Semorinemab Fails to Show Efficacy in Early Alzheimer’s Phase 2 Trial

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Note: This story was updated Oct. 12, 2020, to note that semorinemab is intended to target phosphorylated and non-phosphorylated forms of tau. Semorinemab, a monoclonal antibody against tau, failed ... Read more

September 30, 2020September 30, 2020

$1.76M Grant to Support Trial of Jotrol, Form of Resveratrol, in Early Alzheimer’s

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The National Institute on Aging, a division of the National Institutes of Health, is awarding a $1.76 million, one-year grant to support a Phase 1 clinical trial investigating oral Jotrol as ... Read more

September 28, 2020September 28, 2020

CDC Taps Alzheimer’s Association to Lead National Effort to Slash Dementia Risk

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The Alzheimer’s Association has been chosen to lead a national public health effort aimed at lowering the risk of cognitive decline and dementia. The organization was selected by the ... Read more

September 23, 2020September 23, 2020

Sumifilam Lowers Levels of Multiple Biomarkers of Disease Activity, Trial Shows

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Treatment with sumifilam significantly lowered the levels of multiple biomarkers of disease activity, neurodegeneration, and inflammation in people with mild-to-moderate Alzheimer’s after 28 days of treatment, according to final ... Read more

September 21, 2020September 21, 2020

Specific Tau Protein Shows Potential as Blood Biomarker in Early Studies

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A specific form of the tau protein, called phosphorylated-tau-217 or p-tau217, may function as a blood biomarker of Alzheimer’s disease, allow the development of blood tests to accurately diagnose the disease ... Read more

September 16, 2020September 16, 2020

Theme for World Alzheimer’s Month Is ‘Let’s Talk About Dementia’

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Events are underway to mark World Alzheimer’s Month, observed every September to raise global awareness about the disease and challenge the stigma regarding dementia. September 21 has been designated World ... Read more

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