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June 26, 2019June 26, 2019

Antibiotics Altering Gut Bacteria Reduced Alzheimer’s Symptoms, But Only in Male Mice, Study Shows

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Long-term antibiotic treatment, aimed at altering the bacterial population in the gut, was found to reduce the inflammation and amyloid plaque formation that is a hallmark of Alzheimer’s disease ... Read more

June 24, 2019June 24, 2019

New Genentech Study to Investigate Familial Alzheimer’s Progression and Response to Crenezumab

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Genentech, a subsidiary of Roche, has launched a new substudy to learn more about the progression of early-onset familial Alzheimer’s disease, as part of its ongoing Alzheimer’s Prevention Initiative (API) ... Read more

June 21, 2019June 21, 2019

1st U.S. Patient Enrolled in Phase 2a Trial Evaluating Vafidemstat for Alzheimer’s

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A Phase 2a trial testing Oryzon’s investigational therapy vafidemstat for Alzheimer’s disease has enrolled its first patient in the U.S. The trial (NCT03867253), called ETHERAL-US, is an extension of ... Read more

June 19, 2019June 19, 2019

Vaccine Reduces Tau Tangle Formation, Improves Cognitive Functioning in Alzheimer’s Mouse Model

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A vaccine produced using virus-like particles was able to improve cognitive functioning and reduce the accumulation of tau protein aggregates — a hallmark of Alzheimer’s disease — in a ... Read more

June 17, 2019June 17, 2019

Presence of Mouth Bacteria Linked to Risk of Alzheimer’s, Study Shows

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A connection discovered between Alzheimer’s and the bacteria that cause gum disease suggests that improved oral hygiene may decrease the risk of developing the disorder, a study reports. The ... Read more

June 14, 2019June 14, 2019

AxoSim Licenses Mini-Brain Technology to Pursue Therapies for Alzheimer’s, Other Disorders

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AxoSim has acquired exclusive rights to lab-grown brain miniatures, coined “Mini-Brain,” a technology developed at Johns Hopkins University that uses stem cells to create models of the human brain in a ... Read more

June 12, 2019June 12, 2019

Host of Activities Planned for Alzheimer’s and Brain Awareness Month

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Scores of efforts to mark June’s Alzheimer’s & Brain Awareness Month are designed to raise funds and visibility around the degenerative brain disease and related disorders, and the estimated ... Read more

June 10, 2019

High Levels of ‘Bad’ Cholesterol Linked to Increased Risk of Early-onset Alzheimer’s, Study Suggests

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High levels of “bad” cholesterol, known as low-density lipoprotein (LDL), might increase the risk of developing early-onset Alzheimer’s disease, a study suggests. The study, “Association of Early-Onset Alzheimer Disease ... Read more

June 7, 2019June 7, 2019

ProMIS’ PMN310 Antibody Candidate Shows Greater Effect, Less Risk Than Other Therapies, According to Data

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ProMIS Neurosciences’ candidate PMN310 can specifically target toxic clusters of soluble amyloid-beta protein, and be safely administered at high doses with reduced risk of characteristic Alzheimer’s brain changes or ... Read more

June 5, 2019June 5, 2019

Alzheimer’s Diagnostics Accelerator Program Awards Nearly $3.5M to Develop Early-detection Methods

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Selected through the Alzheimer’s Drug Discovery Foundation’s (ADDF) Diagnostics Accelerator program, four scientists will share nearly $3.5 million to develop new biomarkers for early detection of Alzheimer’s disease and related dementia. ... Read more

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