News

ProMIS Biotech Hopes to Prove Amyloid Theory in Alzheimer’s with New Targeted Therapies

In the wake of the failure of the investigational drug solanezumab, which stirred the debate over whether the prevailing amyloid theory of Alzheimer’s disease is still a viable working hypothesis, ProMIS Neurosciences announced their contribution to Alzheimer’s amyloid-related drug development. The announcement was accompanied by a commentary interpreting…

Menopause May Be Reason More Women Develop Alzheimer’s Than Men

Women perform better than men on all memory measures but these sex differences tend to disappear as women age and enter menopause, according to a study published in the journal Menopause. These findings highlights the importance of ovarian hormones in maintaining memory function and could explain the reason why women are almost twice as likely as men to develop Alzheimer’s disease.

Failure of Lilly’s Solanezumab Not Seen as Conclusive Proof That Amyloid Theory Is Flawed

The Alzheimer’s community lamented Eli Lilly’s recent announcement that its experimental therapy solanezumab failed to demonstrate efficacy in treating the disease in recent clinical trials. In the announcement, released Nov. 23, Lilly said it would not pursue regulartory approval for the drug. Solanezumab’s inability to demonstrate effectiveness in people with mild demential due to…

Alzheimer’s Association Grant Furthers Research into Obesity, Brain Aging and Dementia

The Alzheimer’s Association has awarded a $118,673 grant to a researcher at Boston University School of Medicine to study how obesity affects brain aging and, potentially, a person’s risk of Alzheimer’s disease or dementia. The researcher, Claudia Satizabal, has been associated for several years with the Framingham Heart Study, working with Dr.

Anavex’s Experimental Alzheimer’s Treatment Prevents Mental-acuity Decline in Clinical Trial

Anavex Life Sciences reported that its experimental drug Anavex 2-73 prevented further decline in mental capacity in a small Phase 2a trial involving 32 patients with mild to moderate Alzheimer’s disease. Although the trial was not designed to prove the treatment’s effectiveness, after about 10 months, patients had the same mental acuity…