A recent study published this week in Nature has revealed that the “seeds” of Alzheimer’s disease and related brain disorders may be transmitted by direct tissue transplantation. The results from the study entitled “Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy”, coupled with…
Results from the largest nationwide study investigating long-term high-dose resveratrol in patients with mild to moderate Alzheimer’s disease (AD) showed that a specific a biomarker that declines with disease progression was stabilized in patients who received resveratrol in its purified form. The results, published online in Neurology,…
In a new study entitled “Human umbilical cord blood-derived monocytes improve cognitive deficits and reduce ß-amyloid pathology in PSAPP mice” an international team of scientists showed that infusion of human umbilical cord blood cells (HUCBCs) into a mice model of Alzheimer’s disease improves animals’ cognitive performance by clearing amyloid-beta (Aβ)…
A new study from Michigan State University which aims to pinpoint the early signs of Alzheimer’s disease among Latinos and Hispanics, recently received a 5-year research grant from the National Institute on Aging worth $5.67 million. “Current thinking is it takes decades for Alzheimer’s disease to develop, so we are turning the…
In a new study entitled “Human ApoE Isoforms Differentially Modulate Glucose and Amyloid Metabolic Pathways in Female Brain: Evidence of the Mechanism of Neuroprotection by ApoE2 and Implications for Alzheimer’s Disease Prevention and Early Intervention” researchers reported a breakthrough discovery when they showed ApoE2 human protein is a…
New research presented during the 14th International Conference on Endothelin: Physiology, Pathophysiology and Therapeutics, focused on the effects of IRL-1620 in a rat model of Alzheimer’s disease (AD). The compound, which acts on the endothelin B (ETB) receptor, reduced learning and memory deficits and oxidative stress in the animals, showing potential as an AD…
A gene signature that could be used to predict the onset of diseases, such as Alzheimer’s, years in advance has been developed in a study published in the open access journal Genome Biology. The objective of the study, entitled “A novel multi-tissue RNA diagnostic of…
In a newly published paper in the Neurology journal entitled “Type 2 diabetes mellitus and biomarkers of neurodegeneration”, scientists from Australia found that neurodegenerative disease related dementia could be linked to type 2 diabetes. Neurodegenerative disorders occur as a consequence of a progressive loss of structure/function…
In a new study entitled “Genetic Analysis of Association Between Calcium Signaling and Hippocampal Activation, Memory Performance in the Young and Old, and Risk for Sporadic Alzheimer Disease” a team of researchers discovered a common group of genes that control human memory performance in healthy young and old…
Alzheimer’s Disease (AD) has been a topic of extensive research over the past three decades. The main focus of many studies has been the neurotoxicity associated with the accumulation of insoluble proteinaceous complexes in the brain. Closer examination has revealed these complexes to be plaques formed due to aggregation of…
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