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A recent study titled ”Individuals with Alzheimer’s disease exhibit a high prevalence of undiagnosed impaired glucose tolerance and type 2 diabetes mellitus,” conducted by Scott Turner MD, PhD from Georgetown University and colleagues, found that 43% of Alzheimer’s disease (AD) patients have undiagnosed impaired glucose intolerance. The findings…

A recent study published in the Journal of Alzheimer’s Disease titled “A Clinical Study of Lupron Depot in the Treatment of Women with Alzheimer’s Disease: Preservation of Cognitive Function in Patients Taking an Acetylcholinesterase Inhibitor and Treated with High Dose Lupron Over 48 Weeks“ showed that women…

A research article, titled, “Blood-Brain Barrier Breakdown in the Aging Human Hippocampus” published in the journal Neuron by a team of investigators from the Zilkha Neurogenetic Institute (ZNI) at the University of Southern California (USC) Keck School of Medicine used high-resolution MRI analysis…

Pharnext, a biopharmaceutical company that develops therapeutics called pleodrugs that simultaneously target multiple key disease pathways for serious orphan and common neurological diseases, recently announced the pre-clinical findings of their ongoing Phase 2 clinical trial designed to examine the efficacy and safety profile of on of their pipeline pleodrugs, called…

AC Immune SA recently announced it has signed an exclusive worldwide license agreement and collaboration contract with Janssen Pharmaceuticals, Inc. to develop and commercialize anti-Tau vaccines to treat Alzheimer’s disease. According to the contract, Janssen Research & Development, an affiliate of Janssen Pharmaceuticals, Inc., will advance the development of the vaccine ACI-35 which is…

A team of researchers from Japan found that Alzheimer’s symptoms can be reduced when sugars are averted from binding to one of the disease key enzymes, named BACE1. The study entitled “An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer’s disease“, was published…

On December 2014, scientific experts in the fields of both cardiovascular diseases and Alzheimer’s disease (AD) met in Chicago to discuss the link between vascular risk factors and dementia in AD. The event was organized by the Alzheimer’s Association, with scientific input from the National Institutes of Health’s National…

Patients receiving treatment to correct or control atrial fibrillation, and end up being “overtreated” for a long period of time with anti-clotting medication warfarin, in combination with antiplatelet treatments aspirin or clopidigrel, may have an increased risk of developing dementia or Alzheimer’s disease according to a study presented at the American Heart Association’s…

A team of researchers from Australia aimed to determine the occurrence of eating abnormalities in subtypes of frontotemporal dementia (FTD) besides the well established behavioral variant of frontotemporal dementia (bvFTD). The study entitled “Quantifying the Eating Abnormalities in Frontotemporal Dementia”, was recently published in…

A research team from the Wake Forest Baptist Medical Center developed a form of insulin intended to be delivered via nasal spray that can have positive results on mental capabilities, such as the working memory of adults suffering from Alzheimer’s disease and other mental and cognitive impairments. The study examined the nasal spray’s effects on 60 adults diagnosed with amnesic mild…