A Phase 2b study of oral neflamapimod in treating mild Alzheimer’s disease met its secondary goals of statistically significant drops in phospho-tau and tau protein levels in the cerebrospinal fluid (CSF) of treated patients compared to those given a placebo, EIP Pharma announced. But the trial failed to show evidence of…
EastGate announced plans to expand its liquid insulin delivery platforms, used to treat type 2 diabetes, for use in a possible pilot trial in people with early onset Alzheimer’s disease. “Alzheimer’s disease, along with diabetes, is growing at a rapid pace and simple and effective solutions with existing proteins could…
An experimental vaccine targeting the toxic form of tau protein reduced cellular tangles in the brain — a hallmark of Alzheimer’s — and eased behavioral and motor defects in a mouse model of the disease, a study showed. By generating high levels of anti-tau antibodies, this vaccine…
T3D Therapeutics has secured the needed funding to move forward with its Phase 2 trial testing T3D-959 as a potential treatment for people with mild-to-moderate Alzheimer’s disease. The total funding includes $15 million from an investor, in addition to a $9 million award from the…
Efforts are underway this month to focus attention on Alzheimer’s (AD), a disease that, along with other forms of dementia, affects some 44 million people globally and is rapidly growing in prevalence. During November in the U.S., Alzheimer’s Awareness Month observances include online tributes to caregivers, listings of…
Oligomannate (GV-971), a compound derived from marine brown algae that promotes a healthy gut microbiome, is now conditionally approved in China to treat mild to moderate Alzheimer’s disease (AD), making it the first new disease therapy approved anywhere since Allergan’s Namenda (memantine) in late 2003. The decision was…
A diet that is high in salt can cause dementia in mice by promoting a buildup of plaques of the protein tau, which is also associated with Alzheimer’s disease, a new study shows. The study, titled “Dietary salt promotes cognitive impairment through tau phosphorylation,” was published in …
Treatment with INmune Bio‘s lead candidate XPro1595 can help decrease neuroinflammation and amyloid beta accumulation triggered by a diet high in sugar and fats, according to results from a mouse model of Alzheimer’s disease (AD). Malú Tansey, PhD, professor of neuroscience and director of the Center for…
Landline-style phone service provider teleCalm will use a $100,000 award to advance its new phone service for dementia patients, which helps keep people with Alzheimer’s and related conditions safely connected with family and friends. The Diamond Award was presented by the Austin, Texas offices of MassChallenge, a…
Scientists have developed a simple blood test that may help clinicians identify whether a person has accumulations of abnormal amyloid protein deposits in the brain — an event linked to an Alzheimer’s diagnosis. This new laboratory test may represent an alternate diagnostic tool to other expensive brain…
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