News

A diet rich in phosphatidylcholine, a form of the choline found in foods like eggs and meat, was linked to a lower risk of dementia and better memory skills in middle-aged men in Finland, a recent study reports. These findings suggest that choline helps to support cognitive processing, and verbal and visual…

Compared to regular amyloid imaging, fluorodeoxyglucose positron emission tomography (FDG PET), an imaging technique that quantifies brain function by measuring glucose levels, can better assess the progression and severity of cognitive decline in people with Alzheimer’s, and also cognitive impairment, researchers have found. Their study, “18F-FDG Is…

People with high blood pressure, or hypertension, during midlife are at a greater risk of developing dementia, irrespective of their blood pressure later on, a long-term follow-up study suggests. The study, “Association of Midlife to Late-Life Blood Pressure Patterns With Incident Dementia,” was published in the…

Alkahest’s experimental blood-derived protein GRF6019 helps maintain cognition and function in mild to moderate Alzheimer’s disease patients, results of a six-month Phase 2 clinical trial show. “These top-line results indicate a potential benefit of this plasma protein fraction in slowing the progression of cognitive decline in patients with…

Blood levels of certain molecules— metabolites and amino acids — may help to identify people with Alzheimer’s disease who are more likely to improve their cognitive skills in response to aerobic exercise, a study suggests. These results were shared in the poster “Plasma Metabolites to Predict Response to Exercise in…

AC Immune is launching a Phase 1b/2a clinical trial to evaluate an investigational anti-tau vaccine called ACI-35.030 as a potential disease-modifying treatment for Alzheimer’s disease and other disorders characterized by the accumulation of tau protein. The presence of abnormal aggregates of beta-amyloid and tau proteins in the brain…

To foster the cognitive stimulation of its Alzheimer’s disease (AD) residents, an Arkansas senior living center collaborated with the University of Arkansas – Fort Smith (UAFS) to produce recreational 3D-printed items. A set of large-scale, lightweight, and colorful plastic nuts and bolts were made especially for those…

AZTherapies has completed enrollment for its Phase 3 COGNITE trial, testing the safety and efficacy of its investigational ALZT-OP1 for the treatment of early Alzheimer’s disease (AD). A total of 620 participants were enrolled following the screening of 1,800 patients, the company said. “With the COGNITE trial…

  A mutation in a gene linked to familial Alzheimer’s disease promotes the disease by reducing the points of contact between nerve cells and impairing neuronal communication, a study has found. A chemical compound, called EVP4593, partially rescued the mutation’s negative effects, suggesting it may hold a potential therapeutic…

The University of California, Berkeley (UC Berkeley) will receive an expected $47 million in a federal grant that will add advanced brain imaging to a pivotal study to determine whether lifestyle modifications can protect memory in those at risk of developing dementia. With the five-year grant from the…