ProMIS Neurosciences announced plans to initiate the development of its lead antibody candidate, PMN310, as a potential treatment for Alzheimer’s disease. The investigational therapy is expected to enter clinical Phase 1 trials in 2019. PMN310 is a humanized antibody that attacks only toxic forms of the amyloid beta protein linked to Alzheimer’s, not its…
COR388, Cortexyme‘s investigational compound to treat Alzheimer’s, was safe and well-tolerated in healthy volunteers taking part in a Phase 1 clinical trial, the company announced. COR388 is a first-in-class bacterial protease inhibitor designed to target a specific bacteria that has been identified in both the brain tissue and cerebrospinal…
Sokhey announced it recently launched Swann VR, the world’s first virtual reality memory training device specifically designed for people with Alzheimer’s disease. The company, and product, were created by Taegh Sokhey, a Northwestern University student planning to start medical school. “Patients now have an effective tool that they can…
Eli Lilly and AstraZeneca announced that they are stopping two global Phase 3 trials of lanabecestat, an amyloid beta-targeting treatment candidate for Alzheimer’s, because of an apparent lack of benefit. Safety was not of concern in either trial. The decision follows recommendations by an independent data monitoring…
The Boston Red Sox hosted Cure Alzheimer’s Fund at a recent baseball game against the Detroit Tigers to raise awareness about Alzheimer’s and bring attention to the nonprofit group’s support for research into new treatments and ways of preventing or curing this disease. The event included a ceremony…
Treatment with the investigational compound elenbecestat reduced brain amyloid beta levels and was safe and well-tolerated, according to Phase 2 clinical trial results. The presence of amyloid beta plaques is a major characteristic of the brains of Alzheimer’s disease patients. Amyloid beta is produced through the work of a key…
June is World Alzheimer’s and Brain Awareness Month, and James E. Galvin, MD, MPH, a leading neuroscientist and associate dean at Florida Atlantic University’s Charles E. Schmidt College of Medicine, has compiled a list of myths and truths about the disease. According to Galvin, some…
Medications for type 2 diabetes may help treat symptoms of Alzheimer’s, as these two conditions share common disease mechanisms, according to recent research. Fernanda De Felice, PhD, an associate professor at Federal University Rio de Janeiro, Brazil presented her team’s findings, titled “Molecular connections between Alzheimer’s disease and Type 2 diabetes,”…
Cognition Therapeutics has received two multi-year grants from the National Institute on Aging (NIA) totaling $6.6 million to fund two clinical studies of Elayta (CT1812), Cognition’s lead candidate for the treatment of mild-to-moderate Alzheimer’s disease. Elayta is a brain-penetrating small molecule with a unique disease-modifying mechanism of…
A Phase 1 trial to evaluate the safety and effectiveness of Longeveron’s allogeneic mesenchymal stem cells (LMSCs) in patients with Alzheimer’s disease is currently looking for participants, the biopharmaceutical company announced. Eligible participants must be between 50 and 80 years old, with a confirmed diagnosis of Alzheimer’s disease…
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