Data from a Phase 2b clinical trial showing that vTv Therapeutics‘s investigational drug, azeliragon, slows cognitive decline in patients with mild Alzheimer’s disease were presented at the Alzheimer’s Association International Conference 2016 in Toronto this week. Azeliragon is a drug that blocks the receptor RAGE (Receptor for Advanced Glycation Endproducts) in…
On July 26, a different kind of happening interrupted the usual bustle of activity at this year’s Alzheimer’s Association International Conference (AAIC 2016) in Canada. Attending scientists became the first viewers (at a sneak-peek preview before the North American premiere) of a new kind of full-length documentary film — one that reveals untold…
Researchers at the University of Sussex in England have built a protein closely resembling amyloid-β, except for the fact that it is not capable of aggregating. The new protein, described in a report titled, “A critical role for the self-assembly of Amyloid-β1-42 in neurodegeneration,“ published in the…
Each year on World Brain Day, July 22 the year, the World Federation of Neurology (WFN) dedicates a brain awareness campaign to a different topic. Tomorrow’s will draw our attention to the aging brain — and the diseases that damage it. The campaign hopes to be a wake-up call for politicians and…
North Carolina-based Muses Labs will show its latest technology and services July 24-28 at the Alzheimer’s Association International Conference (AAIC) 2016 in Toronto, Canada. Expected to spur most interest is a presentation by the company’s chief technology officer, John Q. Walker — results from a pilot study of the MEND Protocol, a…
That running can boost our memory to the same degree or more than brain training is an old observation that still puzzles scientists worldwide. But a new study by National Institute on Aging scientists is providing information about how that happens and emphasizing that to keep memory from fading, people should keep running. The study, “…
California-based researchers from the Buck Institute for Research on Aging created a method capable of screening substances that might be effective in age-related conditions such as Alzheimer’s disease — with the help of roundworms. The new tool, presented at the Allied Genetics Conference in Orlando, Florida, on July 15,…
A simple number naming test can identify those with cognitive impairment among elderly individuals, clearly differentiating patients with dementia and people with mild cognitive impairment from cognitively healthy people. The study, “Screening Utility of the King-Devick Test in Mild Cognitive Impairment and Alzheimer Disease Dementia,” published in…
Amyloid-β plaques accumulating in the brain alone are not enough to cause the dementia that characterizes Alzheimer’s, new research from Johns Hopkins University argues. Instead, a second blow — molecular pathways that ultimately cause tau proteins to form tangles inside nerve cells — is also needed for neurons to degenerate. The study, “The…
A study at the Indiana University Center for Aging Research, exploring how screening seemingly healthy older people for dementia impacts family members, has been awarded a $126,000 grant by the National Institute on Aging. The study, called “Effects on Families of older adults Experiencing Cognitive…
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