Studies have shown that women suffer a higher risk of developing dementia than men. Now, a study reports that this gender difference seems to be mirrored by molecular changes in brain proteins, raising prospects of identifying better treatments for both men and women. “The number of dementia patients is projected to triple…
In September 2015, a study published in the journal Nature significantly stirred the scientific community and made people around the world understandably alarmed. The research suggested that Alzheimer’s disease might be transmittable through injections of the disease-driving protein amyloid-β. Researchers all over the world now race to further investigate these…
Two previously failed drug candidates, Eli Lilly’s Solanezumab and Roche’s Gantenerumab, are again under clinical study for Alzheimer’s disease. Both drugs are immunotherapies targeting amyloid-beta in the brain, a target that researchers — including Dr. Michael Geschwind, who spoke with Alzheimer’s News Today — think has the potential to revolutionize…
An editorial by a large number of senior Alzheimer’s researchers urges the scientific community to take a serious look at evidence pointing to the contribution of microbes in the development of Alzheimer’s disease – and calling for more clinical research. Published online in the Journal of Alzheimer’s Disease by…
The buildup of amyloid beta plaques in Alzheimer’s disease is believed to result from patients’ inability to break down the protein. But a new study from Lund University, Sweden, showed that overproduction of amyloid beta is more common than previously thought, giving a more nuanced picture of Alzheimer’s pathology. A small number of Alzheimer’s…
Tel Aviv University and Harvard researchers have found a new biomarker for cognitive aging and Alzheimer’s disease (AD). Diagnosing Alzheimer’s is not an easy task. The process employs measurements of memory impairment, cognitive skills, functional abilities, and behavioral changes, as well as brain imaging and analyses of the cerebrospinal fluid.
While there is abundant evidence that seafood consumption protects from the development of dementia, little is known about the effects of mercury — a heavy metal present in seafood — on the risk of Alzheimer’s disease. A new study shows that seafood mercury does not at all alter disease risk in older adults.
A study from Tel Aviv University found that the IGF-1 receptor, associated with an increased lifespan in mice, is mediating hyperactivity in the hippocampus of the brain. Hippocampal hyperactivity is linked to conditions that increase the risk for Alzheimer’s disease (AD), and the findings may pave the way for new AD treatments…
Researchers at the Scintillon Institute for Biomedical and Bioenergy Research, San Diego, have discovered that the high blood sugar levels that mark type 2 diabetes and the plaque-forming β-amyloid protein found in Alzheimer’s disease (AD) cause the same alterations in several brain enzymes. The findings explain the association long observed between AD and diabetes. The results,…
British researchers recently identified a protein driving brain inflammation, CSF1R, which they think may be the driving force behind the progression of Alzheimer’s disease (AD). The study, “Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer’s-like pathology” and published in the journal Brain, could be a significant step forward in…
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