Author Archives: Magdalena Kegel

Alzheimer’s Disease First Steps Revealed by Mouse Brain in a Dish

Using slices of mouse brain tissue kept alive in a lab dish, scientists have identified the earliest molecular changes leading to Alzheimer’s disease. The findings, showing how early alterations in brain amyloid-β balance causes nerve connections called synapses to die, might allow scientist to target the mechanisms and develop therapies to…

Small Test with Ten Alzheimer’s Patients Shows Program Reversed Early Cognitive Decline, Improved Symptoms

Scientists at the Buck Institute for Research on Aging recently demonstrated that memory loss for patients with early Alzheimer’s disease can be reversed — a feat the research team managed through a 36-point approach called metabolic enhancement for neurodegeneration. The multidisciplinary program is the first to show that cognitive decline and…

Alzheimer’s Inhibitor BACE to Enter Worldwide Phase 2/3 Trial

Alzheimer’s Therapeutic Research Institute (ATRI) at the University of Southern California, and Janssen Research & Development will collaborate for a  Phase 2/3 clinical trial of Jansen’s BACE blocker intended to delay or even prevent Alzheimer’s symptoms. The BACE blocker is a drug that prevents the action of an enzyme involved in…

Keeping Busy May Also Keep Dementia at Bay by Improving Cognitive Skills

A somewhat hectic schedule might protect a person from cognitive decline, a study from the University of Texas at Dallas reported. Busy people had better processing speed, working memory, episodic memory, and reasoning and language skills independent of age and education, indicating that a busy lifestyle might boost neuronal connections. Busy lifestyles — a…

Alzheimer’s Molecules Can Be Detected by Researcher-Developed Nanoscale Biosensor

Brazilian researchers have developed a nanoscale biosensor that can detect molecules linked to Alzheimer’s, as well as other neurodegenerative diseases, and certain cancers. The system marks a new era where highly sensitive, inexpensive, and portable devices might become accessible by healthcare professionals, and in settings without access to traditional resources. The sensor,…