News

Vanderbilt University researchers have developed a potential therapy for Alzheimer’s disease (AD) that has shown promising results in brain health. The investigative treatment, a molecule called VU319, is expected to fill a long-needed gap for Alzheimer’s patients by improving memory, attention, and brain functioning. The U.S. Food and Drug Administration…

A lack of energy in brain cells called microglia might explain why people with mutations in the TREM2 gene are more likely to develop Alzheimer’s disease, according to a mouse study that showed exhausted microglia lacked the capacity to confine amyloid plaques. By restoring the energy levels in these cells,…

Consuming alcoholic beverages on a daily or near-daily basis was linked to a cognitively healthy and longer life in older adults in a study by led researchers at the University of California San Diego. Moderate to heavy (but not excessive) drinking was defined as up to three daily alcoholic beverages for women…

A functional brain imaging study led by scientists at the Amen Clinics in Newport Beach, California, has qualified differences between women’s and men’s brains with relevant findings for Alzheimer’s disease research. The study, “Gender-Based Cerebral Perfusion Differences in 46,034 Functional Neuroimaging Scans,” appeared in the Journal of Alzheimer’s Disease. Understanding…

A research team from MIT has found a way to reverse memory loss in mice, which may lead to new treatments for patients with Alzheimer’s disease. The findings were reported in a study titled “The Transcription Factor Sp3 Cooperates with HDAC2 to Regulate Synaptic Function and Plasticity in Neurons”…

Loyola Medicine will participate in a landmark $100 million study called “Imaging Dementia – Evidence for Amyloid Scanning (IDEAS)” to evaluate the effectiveness of using positron emission tomography (PET) scans to detect Alzheimer’s disease (AD). The IDEAS (NCT02420756)…

The use of antidepressants in patients with Alzheimer’s disease increased their risk of head injuries, a Finnish study recently found. The risk of head injuries in these patients previously had not been studied. Head injuries are often a consequence of falls in older people.

A student-led team of researchers at Washington University School of Medicine (WUSM) in St. Louis, Missouri, has developed an online app designed to streamline the process of Alzheimer’s disease diagnosis. It provides physicians with more information about patients before they are evaluated in person, enabling physicians to assess and assist patients…

VTv Therapeutics has received another U.S. patent for azeliragon, an Alzheimer’s treatment that targets a receptor involved in the disease’s inflammation. Azekuragan is an antagonist of the advanced glycation endproducts, or RAGE, receptor, meaning that it prevents the receptor from acting. Found in low levels in a healthy brain, RAGE…

The National Institutes of Health has awarded the University of California at Davis a multiyear grant of nearly $14.7 million to pinpoint the reasons why Latinos have higher rates of dementia than other American ethnic groups. Nine other universities will take part in the UC Davis-led study. Researchers will…