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Antibodies that ProMIS Neurosciences created to target molecules associated with Alzheimer’s inhibit the accumulation of the amyloid beta protein that is a hallmark of the disease. The company’s researchers used two computer algorithms, ProMI and Collective Coordinates, to predict amyloid beta misfolding and five disease-specific targets for antibodies, according to a presentation…

A nationwide case-control study conducted by researchers from the University of Eastern Finland found an association between mental and behavioral disorders and Alzheimer’s disease (AD). However, this effect was dependent on the time between the first signs of  psychiatric disorders and the diagnosis of Alzheimer’s. The study, “Hospital-treated mental…

The high concentration of vitamin B12 in Marmite — a distinctly British food spread that many say is an acquired taste — was found to increase levels of gamma–aminobutyric acid (GABA) chemicals in the brain, which may protect against neurological disorders like Alzheimer’s disease, epilepsy or depression. This is according…

The Alzheimer’s Foundation of America (AFA), which represents more than 2,600 member organizations nationwide, testified March 29 at a Senate hearing in Washington that discussed issues related to cognitive decline. The AFA’s brief to the Senate Special Committee on Aging described the state of Alzheimer’s disease and its impact on…

Americans who want to assess their risk for late-onset Alzheimer’s disease may now order $199 genetic tests, now that the U.S. Food and Drug Administration (FDA) has allowed 23andMe to sell such genetic analyses directly to consumers. Besides Alzheimer’s, the Mountain View, Calif., company has received authorization for reports on Parkinson’s disease, hereditary…

New York-based Anavex Life Sciences presented data at the recent 13th International Conference on Alzheimer’s & Parkinson’s Diseases in Vienna showing that its compounds binding to the sigma-1 receptor hold promise in treating Alzheimer’s disease. Besides the well-known accumulation of amyloid beta peptide and the formation of senile plaques, researchers have extensively described the…

So-called “SuperAgers” lose brain volume more slowly than their normally aging peers, protecting them from dementia, according to a new study that proves yet again that Alzheimer’s disease — like other dementias — is not an inevitable fate in predestined individuals. The study, “Rates of Cortical Atrophy in Adults 80…

AXON Neuroscience announced that AADvac1, a vaccine against tau (a protein that accumulates and forms tangles inside neurons in diverse neurodegenerative diseases) showed therapeutic potential in Alzheimer’s disease (AD) and frontotemporal dementia (FTD) in a Phase 1 study. The announcement was made by Matej Ondrus, MD, the company’s medical director, at…

Alzheimer’s disease and other neurological illnesses cost Americans about $789 billion in 2014 — a price tag that will go only up as the country’s elderly population doubles by 2050. Yet the Trump administration’s proposal to cut the budget of the National Institutes of Health (NIH) by $5.8 billion, or 18…

ALZ-801 may be a safe and effective treatment for Alzheimer’s patients with mild disease who carry two copies of the APOE4/4 gene, results of a clinical program indicate. The results are being disclosed in four presentations by the drug’s developer, Alzheon, at the 13th International Conference on Alzheimer’s and Parkinson’s Disease, taking…