News

Researchers have discovered that a genetic elimination of peripheral immune cell populations leads to a more rapid development of amyloid brain plaques (which are present in Alzheimer’s patients), worsening of neuroinflammation, and dysfunction of microglial activity. The study, “The adaptive immune system restrains Alzheimer’s disease pathogenesis by modulating microglial function,”…

Takeda Pharmaceutical Company and partner Zinfandel Pharmaceuticals announced the completion of patient enrollment in the TOMMORROW Phase 3 Clinical Trial, one of the largest studies ever to be executed in mild cognitive impairment and Alzheimer’s disease (AD). Previous research has shown that individuals who develop mild cognitive impairment (MCI) are…

Researchers at Atlanta’s Emory University, under the guidance of neurologist Dr. Allan Levey, are studying the lineage of a specific family whose members are exceptionally prone to the development of late-onset Alzheimer’s disease in the search for new causes, such as novel genetic mutations, biomarkers, and brain changes. The ongoing…

A critical but vulnerable brain region seems to be the first area disturbed by late onset Alzheimer’s disease, and to be a region more essential for preserving cognitive function in later life than previously thought, according to a review, “The Locus Coeruleus: Essential for Maintaining Cognitive…

Researchers at the Johns Hopkins Bloomberg School of Public Health have developed “mini-brains” that may present a more accurate and effective way of testing new drugs for many neurological disorders, such as Alzheimer’s disease. These human cell-derived structures, which represent an existing new alternative to animal testing, were recently discussed in a…

Scientists have discovered the anti-cancer drug bexarotene may target the first step in the toxic chain activity that leads to the death of brain cells, paving the way to new Alzheimer’s therapies. The study, conducted by an international team of researchers from the University of Cambridge in England, Lund University in…

Researchers have discovered that the skeleton surrounding the nucleus of brain cells is dysfunctional in Alzheimer’s disease patients, which could lead to neuronal death. The study, “Lamin Dysfunction Mediates Neurodegeneration in Tauopathies,” was published in Current Biology. The lamin nucleoskeleton that surrounds the nucleus of cells is important in the…

As part of Allianz Championship week in Boca Raton, Florida, Allianz encouraged golf enthusiasts to share their favorite golf memories on Facebook, Twitter, Instagram and other social media sites — using the hashtag #AllianzBirdies — to raise awareness of the Alzheimer’s Association and its work. Two company groups —  Allianz Life and Allianz Global…

Researchers at Harvard Medical School and the Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology have developed a system that allows them to study individual human neurons and other nervous system cells. Researchers have identified the subpopulations of cells responsible for the secretion of Alzheimer’s disease-relevant factors…

Tel Aviv University and Harvard researchers have found a new biomarker for cognitive aging and Alzheimer’s disease (AD). Diagnosing Alzheimer’s is not an easy task. The process employs measurements of memory impairment, cognitive skills, functional abilities, and behavioral changes, as well as brain imaging and analyses of the cerebrospinal fluid.