A study published in the journal Nature Neuroscience revealed new insights into the role played by astrocytes in neurological disorders such as Alzheimer’s disease. The study was conducted by an international research team and is entitled “Nuclear pore complex remodeling by p75NTR cleavage controls…
Dementia can be defined as a disease which affects the brain’s ability to go through a clear process of thinking, reasoning and remembering. The disease can affect several parts of the brain and patients with dementia may face difficulties dealing with language, memory loss, impaired visual-spatial orientation, loss of problem…
This week, Ohio State University (OSU) researcher, Dr. Rene Anand, PhD, MS whose laboratory is focused on studying how genes and the environment interact to increase susceptibility to neurodevelopmental, neuropsychiatric and neurodegenerative disorders in an effort to develop brain organoids (three-dimensional organ-bud grown in a laboratory) to study…
An international team led by researchers at The Rockefeller University and Columbia University recently published in the journal Nature Medicine a novel mechanism through which it is possible to decrease the production of beta-amyloid protein, a key factor in Alzheimer’s disease development. The study is…
A research article, titled, “Subtle Cognitive Decline and Biomarker Staging in Preclinical Alzheimer’s Disease” recently published in the Journal of Alzheimer’s Disease by a team of investigators from the University of California in San Diego (UCSD) School of Medicine and Veterans Affairs San Diego…
A study recently published in the journal Neuropsychopharmacology revealed that the inhibition of a gene called phosphodiesterase-4B (PDE4B) in mice enhances the animals’ cognitive abilities. The work was conducted by an international team of researchers and is entitled “Specific Inhibition of Phosphodiesterase-4B Results in Anxiolysis…
The biggest risk factor for Alzheimer’s disease (AD) is aging. After the age of 65 the risk doubles every 5 years, with over 40% of those aged 85 and older expected to develop the debilitating condition. Scientists at the Washington University School of Medicine in St. Louis managed to identify some of the crucial changes that occur in the brain…
A scientist from the University of Oklahoma is developing a new therapy to address Alzheimer’s disease using “biopharmaceutical proteases” to destroy the toxic plaque that piles up in the brain of Alzheimer’s patients. This approach will have significantly lower costs in the treatment of the disease while at the same time it has the potential to…
In a recent study published in the journal Alzheimer’s & Dementia a team of researchers found that eating a group of certain foods known as the MIND diet may slow cognitive decline among aging adults, even when the person is not at risk of developing Alzheimer’s…
Soon-to-be former partners in a promising Alzheimer’s research program, Eli Lilly and Co. and the University of California San Diego (UCSD) have moved a step closer to ending the contract that covers the Anti-Amyloid Treatment in Asymptomatic Alzheimer’s disease (A4) study, a groundbreaking clinical trial that aims to test solanezumab. This Phase…
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