News

In a recent study entitled “Pharmacological chaperones stabilize retorter to limit APP processing,” the authors report that pharmacologic chaperones have a highly positive impact on a multiprotein complex — the retromer — that has been linked to Alzheimer’s disease. The study was published in the April issue…

In patients suffering from Alzheimer’s disease or dealing with the aftermath of a stroke, a lack of orientation — as if their inner perception of the world in which they always lived in just disappeared — is common. Researchers from the University of California, San Diego School of Medicine induced…

In a research article entitled “Primary age-related tauopathy (PART): a common pathology associated with human aging,” recently published in the Acta Neuropathologica, researchers uncovered new insights into an Alzheimers-related memory disorder. This multi-institutional study, co-led by…

In neurodegenerative disorders such as Alzheimer’s Disease, the loss of memory is often a defining symptom. In a study entitled “FASTKD2 is associated with memory and hippocampal structure in older adults” the authors report to have found a new genetic variant in the FASTKD2 gene that is associated with…

In a recent study entitled “Longitudinal PET-MRI reveals β-amyloid deposition and rCBF dynamics and connects vascular amyloidosis to quantitative loss of perfusion” the authors developed a new imaging protocol that allows detection and examination of Alzheimer’s Disease typical beta-amyloid plaques. The study was published in the online issue of…

Researchers at Massachusetts General Hospital (MGH) are looking to flip the molecular switch for inflammatory diseases such as Alzheimer’s to the “off” position. Masao Kaneki, MD, PhD, in the Department of Anesthesia, Critical Care, and Pain Medicine at MGH, discovered that nitric oxide acts on the protein SIRT1, leading…

The Cigna Foundation announced that is awarding a $196,000 World of Difference grant to the Alzheimer’s Association to support the development of a program dedicated to help early stage patients currently diagnosed with Alzheimer’s and other forms of dementia. LiveWell interactive E-Learning Program is meant to be a…

In a recent study entitled “Anxiety symptoms in amnestic mild cognitive impairment are associated with medial temporal atrophy and predict conversion to Alzheimer’s disease” the authors report on how people with mild cognitive impairment have higher risk of developing Alzheimer’s, especially if they suffer from anxiety.

A study entitled “A Chaperome Subnetwork Safeguards Proteostasis in Aging and Neurodegenerative Disease” recently published in the journal Cell Reports, identifies a subset of chaperones that protect protein-correct folding in aging brains and neurogenererative diseases, such as Alzheimer’s. In this study, a team of scientists at Proteostasis Therapeutics,…

A novel, potentially disease-modifying treatment for Alzheimer’s disease is set to begin a Phase 2a clinical trial, designed to evaluate efficacy over a time frame of 6 months, across 7 study sites in Australia. ANAVEX 2-73, a pipeline product of Anavex Life Sciences Corp.,…