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Novel Culture System Replicates Alzheimer’s Disease Development; Confirms Amyloid Hypothesis; Should Significantly Reduce Drug Development Time/Cost

An innovative laboratory culture system developed by an international team of investigators led by scientists of the Genetics and Aging Research Unit at Massachusetts General Hospital (MGH) provides the first clear evidence supporting the hypothesis that deposition of beta-amyloid plaques in the brain is the first step in…

New Solution For Repairing Misfolded Proteins in Alzheimer’s

A new study entitled “HSF-1–mediated cytoskeletal integrity determines thermotolerance and life span” published in Science unravels the role of heat shock transcription factor–1 (HSF-1) in aging and associated neurodegenerative diseases, such as Alzheimer’s. Heat shock proteins (HSP) are a group of proteins induced by heat…

Alzheimer’s Disease Culture System Confirms Landmark Hypothesis

A pioneering in vitro culture model of Alzheimer’s disease was established for the first time by researchers from the Genetics and Aging Research Unit at Massachusetts General Hospital (MGH), entitled “A three-dimensional human neural cell culture model of Alzheimer’s disease.” The study, which was recently published in the …

Promising Alzheimer’s Test Enters Next Stage of Development

Amarantus BioScience Holdings, Inc. recently released promising results from the Lymphocyte Proliferation Test (LymPro Test®) blood diagnostic for Alzheimer’s disease (AD) LP-002 study. Amarantus is a biotechnology company focused on research and development of treatments and diagnostics for diseases related to neurodegenerative and apoptosis (programmed cell death) processes that contribute…

Muses Labs Brings Software Expertise to Alzheimer’s Disease Therapeutics

Muses Labs, based at Research Triangle Park in Raleigh, North Carolina, creates software-based systems to enable personalized therapy for the treatment of complex diseases. The company recently announced the development of its first offering for addressing Alzheimer’s disease. The combination therapy it implements is based on a broad understanding…