Denali Therapeutics has begun dosing patients in its Phase 1b clinical trial of DNL747 as a treatment for Alzheimer’s disease. “We are excited to…
Articles by Alice Melão
Inhibiting a protein called NHE6 is a potential strategy to prevent the damaging effect of ApoE4 and the associated risk…
Extracts from three South African plants can help prevent the formation of toxic amyloid protein aggregates known to contribute to…
CavoGene LifeSciences is going to explore a new gene therapy, called SynCav1, that may represent an alternative and attractive…
Commonly used antidepressants known as selective serotonin reuptake inhibitors, or SSRIs, can prevent beta-amyloid aggregation, representing a potential new…
A newly developed antibody targeting a protein called fibrin was seen to prevent inflammation and oxidative stress induced by amyloid…
Fasudil, a chemical inhibitor used to treat strokes, may prevent early nerve cell impairment and sustainment of beta-amyloid damaging effects, opening new therapeutic…
An investigational antibody effectively targeted toxic protein aggregation in the brain of a mouse model of Alzheimer’s disease, improving memory and cognitive…
The absolute 10-year risk of dementia varies according to age, gender, and common variation in the APOE gene, according to…
Flortaucipir, an investigational imaging agent, was able to efficiently detect Tau protein aggregates and related Alzheimer’s disease brain changes,…